Chemistry Technologies Offered
- Photo chemistry: enables unique chemical reactions using light, often creating complex molecules with high precision and efficiency, is valuable for synthesizing API and drug intermediates, improving sustainability and enabling innovative pathways in drug discovery and production.
- Carbohydrate chemistry: focuses on the design and synthesis of carbohydrate-based drugs and therapeutics. Enhanced drug efficacy, targeting, and bioavailability can be achieved by designing carbohydrate analogs or modifying natural sugars of some drugs.
- Linker chemistry: has a critical role in developing antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs), bifunctional molecules targeting the degradation of specific proteins through the recruitment of E3 ubiquitin ligases.
- Deuterium compound chemistry: Deuterated compounds, containing deuterium in place of some hydrogen molecules, can enhance drug stability and metabolic properties.
- RNA chemistry: focuses on short nucleic acid molecules, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), and antisense oligonucleotides, which can regulate gene expression and influence cellular pathways.
- Enzymatic chemistry: Utilizes biological catalysts that accelerate chemical reactions in living organisms. Harnessing enzymes can create more efficient and sustainable chemical processes and develop more complex targeted therapies.
- Isotopic labeling: involves incorporating stable or radioactive isotopes into molecules to track and study drug behavior in biological systems to understand metabolic pathways, drug distribution, and absorption.
- Asymmetric chemistry: focuses on the synthesis of chiral molecules, which are vital in drug development, since many drugs exhibit different biological activities based on their chirality.
- Peptide chemistry: focuses on short chains of amino acids linked by peptide bonds. Advances in peptide chemistry enable the design of novel peptide-based drugs, improving specificity and efficacy thereby enhancing therapeutic strategies.